Hands-down one of the most annoying features of the few Android phones that implement it is the MTP storage standard, which is frustrating on Windows PCs and nearly useless on Mac. Honeycomb and Ice Cream Sandwich devices (and even some Samsung Gingerbread phones) have adopted MTP over the older and generally more reliable USB Mass Storage, much to the consternation of Android users everywhere. Luckily, there's a new project on XDA that gets around it and returns sweet, sweet USB mounting to your Android device and your Mac: Alt Mounter.
Basically, Alt Mounter creates an alternate connection between your phone and your Mac, sidestepping the MTP protocol for a separate connection. You'll need a separate application running on your Mac in addition to the FUSE package. Install the apps on your phone and your Mac, tap the widget on your homescreen and you're good to go with blessedly fast, old-fashioned file transfers.
Currently the program is only available for Mac, but the developer is thinking about creating Windows and Linux versions as well. It's also in beta, so tread with caution. You can download both the app and the OS X program at this file reservoir. Go now, Mac users, and transfer files with reckless abandon! (And by the way, if you don't want to mess with any extra desktop software, try AirDroid and a local WiFi network.)